Figure 3
The Primo Vascular System (PVS). (A) Schematic representation of a primo vessel (PV). The membrane of the PV has high concentration of hyaluronic acid and consists of several subchannels. (B) A subchannel with an endothelium membrane with a rod-shaped nucleus cell. It is described also as having an adventitia that has connective tissue made of collagen. (C) The subchannels carry a liquid, the primo liquid, with cells, microcells, stem cells, and several substances such as hormones and proteins. The cells of the PVS show smooth-muscle Ca2+-excitable cells that are related to the movement. Organ surface PVs and PNs have monocytes eosinophils, mast cells, and macrophages. PNs = primo nodes; PVS = primo vascular system. (Adapted from the study by Kang et al [56].).